GLP-1 stands for Glucagon-Like Peptide-1, which mimic the body's a natural incretin hormone. This hormone is produced in the intestines and helps your body regulate blood sugar in response to food intake. It also slows digestion which, in turn, helps you feel fuller longer and can lead to weight loss and lower blood sugar levels.
There are currently two major players in the GLP-1 game. They are Semaglutide, which is a GLP-1 receptor agonist. Semaglutide mimics the effects of the hormone that helps regulate appetite and insulin levels after meals. The other is Tirzepatide, which is a GIP/GLP-1 DUAL receptor agonist, combining effects of both GLP-1 and GIP hormones to enhance glucose control and weight loss.
How are GLP-1 medications administered?
Both Semaglutide and Tirzepatide are injected subcutaneously once a week. The injection needle is tiny and most of our patients report little or no discomfort administering their own medication. Your treatment will start with a low dose and gradually increase over weeks or months. This can help your body adjust to the medication and minimize side effects.
Which GLP-1 Medicine is right for me?
Clinical studies indicate that Tirzepatide (a.k.a ZepboundTM or MounjaroTM) may lead to more significant weight loss compared to Semaglutide, owing to its dual action. This can be a crucial factor for patients with more substantial weight loss goals. However, Semaglutide (a.k.a. OzempicTM) is also proven to be a significant help in weight loss.
The choice between Semaglutide and Tirzepatide depends on several factors, including:
Medical History: Abby will take into account your overall health, any existing medical conditions, weight loss goals and your history of diabetes management.
Effectiveness: Both medications help blood sugar control and aid in weight loss. Abby will choose a treatment plan that is best for you while taking into consideration the latest medical studies and research data.
Side Effects: Abby will educate you on the of the side effect profiles of both medications prior to starting any GLP-1 medication. Patient education is a key priority.
These medications are not one size fits all. During your consultation Nicole and Abby will take a complete medical history and draw a series of labs which are essential to determine which medication is better suited for you. You will be continually monitored during your treatment.
What are the side effects of GLP-1 medications?
As always, side effects should be considered before beginning any new medication. In this case, both medications may cause side effects like nausea, vomiting, constipation, dizziness and digestive issues. The good news is many patients experience little to no side effects while using these medications.
If you are experiencing uncomfortable side effects Abby and Nicole may suggest:
Dietary Adjustments:
Eat Smaller, More Frequent Meals: Large meals can exacerbate nausea. Smaller, more frequent meals may help.
Avoid High-Fat Foods: Fatty foods can worsen gastrointestinal symptoms.
Stay Hydrated: Drink plenty of water to help manage constipation and prevent dehydration from vomiting or diarrhea.
Medication Timing: Take your medication at a time of day and day of the week when side effects will be least disruptive to your routine.
Physical Activity: Regular exercise can help improve gastrointestinal motility and reduce constipation.
Anti-Nausea Medication: If nausea is severe, Abby may prescribe anti-nausea medication.
Monitor and Report: Keep a diary of your side effects and report them to Abby and Nicole. They may adjust your dose or switch you to a different medication.
Follow-Up: Regular follow-ups are crucial to monitor your response to the medication and make any necessary adjustments to your dosage.
Rest and Relaxation: Ensuring you get adequate rest and manage stress can help mitigate some side effects.
Patient Education: Ask questions! We want you to understand the potential side effects and how to manage them. We are here to help you feel in control and prepared.
Are you ready to take control of your Health?
GLP-1 research is booming. GLP-1 medications, primarily known for their roles in managing type 2 diabetes and aiding in weight loss, have shown a range of other potential benefits:
Cardiovascular Health: Reduced Cardiovascular Events: Some GLP-1 medications have been associated with a lower risk of heart attack, stroke, and other cardiovascular events. These medications have also shown modest reductions in blood pressure.
Lipid Profile Improvement: GLP-1 medications can help reduce LDL (bad) cholesterol levels and there is evidence of a positive effect on HDL (good) cholesterol.
Renal Protection: Kidney Function: Some studies suggest that GLP-1 medications may help protect against diabetic nephropathy (kidney damage) by reducing proteinuria (excess protein in the urine) and slowing the decline in kidney function.
Neuroprotective Effects: Cognitive Benefits: Preliminary research indicates that GLP-1 medications might have neuroprotective effects, potentially benefiting cognitive function and offering protection against neurodegenerative diseases like Alzheimer's.
Liver Health: Non-Alcoholic Fatty Liver Disease (NAFLD): GLP-1 medications can help reduce liver fat and inflammation, offering potential benefits for patients with NAFLD.
Inflammation Reduction: Anti-Inflammatory Effects: GLP-1 medications may have anti-inflammatory properties, which can contribute to improved overall health and reduced risk of chronic diseases.
Bone Health: Bone Density: There is some evidence to suggest that GLP-1 medications might have a positive impact on bone density, potentially reducing the risk of fractures and Osteoporosis.
We are excited about the future of GLP-1 medication research and the positive impact they are having on our patients! Join the Emerald Direct Heath family to begin your GLP-1 journey.
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